What have been the most important outcomes of the human genome project? Almost two decades after the human genome was completed, should genetic data still be treated as “exceptional?”

Q2 Discuss the mechanisms, functions, and implications of epigenetic changes during gene regulation, including the possible role of trans- generational epigenetics.

Q3 After reviewing the goals and methods of genetic manipulation of mammals, provide more detail on one approach of interest including how it works and an example where it has been applied.

Q4 Discuss the scope and importance of studying human genetic variation, describing one population-based example and one locus-specific example.

Q5 Discuss the importance of concepts in population genetics to understanding human ancestry, evolution, and patterns of inherited disease.

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