• The pharmacology of NSAIDs and triptans and relate this to the

pathophysiology of migraines.
• Summarise the clinical evidence that supports the efficacy and safety of the classes of drugs for

the treatment of migraines from reviews provided by systematic reviews from evidence based medicine

databases/sources i.e. Cochrane Reviews Database etc. You should provide a summary of the evidence from

these reviews and use the publications on the individual clinical trials for the next section.
• Critically evaluate the clinical evidence to provide an appraisal of the quality of this evidence.